Frank Augustus Sampson OBE CdeG BASc was born in Toronto, Ontario, son of Mr. and Mrs. A. M. Sampson. He attended Central Technical School and graduated from the University of Toronto with a BASc in engineering. While attending university, he served with the RCAF on a reserve basis for two summers before his appointment to the permanent Air Force as a pilot, in 1927.

From 1937 until 1939, Sampson was attached to the Royal Air Force overseas, where he had extensive service in flying boat operations out of the United Kingdom, Malta and Singapore.

In 1940 he was appointed Director of Postings and Careers at Air Force Headquarters, Ottawa. While holding that position he was Canadian Officer in Charge of dealing with the transfer back to the United States of all US nationals serving in the Canadian Armed Forces. For his effectiveness and diplomacy in carrying out this work, the USA government decorated him with the United States Legion of Merit.

In 1942 he was appointed Commanding Officer of No. 2 Service Flying Training School at Ottawa (Uplands) airport, holding the rank of Group Captain. In 1943 he was posted to the United Kingdom and served as Commanding Officer of several stations in the RCAF’s famous No. 6 bomber Group. In recognition of his distinguished service with the RCAF in the UK he was decorated with the French Croix de Guerre with Silver Star.

Early in 1945 he was posted to the staff of "Supreme Headquarters, Allied Expeditionary Forces," where he carried out duties in connection with the liberation of Canadian prisoners of war. Upon completion of that work he was appointed Director of Personnel at RCAF Overseas Headquarters, where he served until repatriated to Canada in April 1946.

On his return to Canada, he became Chief staff Officer, Northwest Air Command Headquarters in Edmonton Alberta. He remained in that post until 1948 when he was named Canadian Air Attaché, to Argentina. In 1951 he was appointed as Air Attaché to France, based in Paris.

In 1946, for distinguished service, Group Captain Sampson was appointed an Officer of the Most Excellent Order of the British Empire (OBE). In March 1955, after 30 years of Air Force service, Group Captain Sampson retired from the RCAF.

In 1935 he married the former Catherine Clare Bate of Ottawa. They had two children; Catherine Bate Sampson and Cameron Walters Sampson.